Anakinra for Treatment-Resistant Kawasaki Disease: Evidence from a Literature Review
نویسندگان
چکیده
منابع مشابه
A child with resistant Kawasaki disease successfully treated with anakinra: a case report
BACKGROUND Kawasaki disease (KD) is an acute self-limited systemic vasculitis of unknown etiology. Intravenous immunoglobulin (IVIG) is an effective treatment and decreases the risk of cardiac complications to less than 5%. In spite of its effectiveness, some children do not respond to this therapy and still develop coronary aneurysms (CAA). The optimal treatment for IVIG non-responsive patient...
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We report an 11-week-old female who presented with Kawasaki disease (KD) complicated by macrophage activation syndrome (MAS). The infant presented to the hospital with persistent fever, cough, diarrhea, and emesis, among other symptoms. Her condition quickly began to decompensate, and she developed classic features (conjunctivitis, rash, cracked lips, distal extremity edema) prompting a diagnos...
متن کاملCorticosteroid therapy for primary treatment of Kawasaki disease – weight of evidence: a meta-analysis and systematic review of the literature
OBJECTIVE Corticosteroids are the treatment of choice in most forms of vasculitis. However, their role in the primary treatment of Kawasaki disease (KD) is controversial. Our aim was to conduct a meta-analysis to assess the clinical course and coronary artery outcome of adding corticosteroids to standard therapy [intravenous immunoglobulin (IVIG) + aspirin] in patients with acute KD. METHODS ...
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SARS-CoV-2 emerging from Wuhan, China is a member of the Coronaviridae family, which has so far infected and killed many people. The SARS-CoV-2 pandemic affected various aspects of life in Iran and Worldwide, and governments have imposed quarantines and travel bans on an unprecedented scale. The virus causes COVID-19, which can spread through close contact with the infected person, contaminat...
متن کاملkawasaki disease; a review article
kawasaki disease is believed to be the commonest vasculitis of medium vessels in asian children. however, the majority of children with kawasaki disease continue to remain undiagnosed perhaps because of the lack of awareness amongst pediatricians. the clinical features of kawasaki disease can be confused with other common conditions such as scarlet fever, stevens johnson syndrome, measles fever...
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ژورنال
عنوان ژورنال: Pediatric Drugs
سال: 2020
ISSN: 1174-5878,1179-2019
DOI: 10.1007/s40272-020-00421-3